Bionovax

Heparin, a most widely used natural medicine for blood anti-thrombosis, is an extract from the mucosa layer of healthy porcine intestines and is a sulfated polysaccharide belonging to the family of glycosaminoglycans (GAG). It is the highest negative charge molecule (the average negative charge of a heparin macromolecule is about -75) within the natural products around the world, which could be related to its anti-coagulation character of the material.

Low-molecular-weight heparin)，
Heparin, with macromolecular weight between 3 and 40 KDa, consists of alternating residues of a uronic acid (either ß-D-glucuronic acid or α-L-iduronic acid) with a hexosamine (α-D-glucosamine) linked by 1-4 glycosadic linkage and covalently bound to serine residues of the core protein. It has various O-sulfo, N-sulfo, and N-acetyl substituents that are usually heterogeneously distributed along the GAG chains. The most common repeating disaccharide sequence occurring in heparin is the tri-sulfated disaccharide with a sulfonate group at position 2 of the uronate residue and at positions 2 and 6 of the glucosamine residue.

The need of heparin is in greater demand, in kidney dialysis and to prevent blood coagulation at surgeries etc., as human ages.